LRI Research Program

The Long-Range Research Initiative (LRI) was established by the American Chemistry Council in 1999 to demonstrate its commitment to advance scientific understanding of the potential impacts of chemicals on human health and the environment.

By design, the LRI research program does not focus on specific chemicals but rather identifies broad areas of scientific investigation that are relevant to the chemical industry and society. The LRI is an extension of the ACC Responsible Care® initiative, the chemical industry’s global voluntary commitment to continuous improvement in environmental, health, safety, and security performance.

The ACC LRI is part of a global LRI program under the auspices of the International Council of Chemical Associations (ICCA) and includes LRI programs supported by the European Chemical Industry Council (Cefic) and the Japan Chemical Industry Association (JCIA). Through the ICCA, these independently managed LRI research programs support complementary areas of scientific investigation with the overall goal to promote improvements in the way that industry, academia, and governments evaluate chemicals.


The mission of the LRI is to identify and fill gaps in our understanding about the hazards posed by chemicals and to improve the methods available for assessing the associated risks.

Its innovative research program is designed to improve the way we address the safety of our chemicals, particularly everyday exposures of consumers to low levels of chemicals and chemical mixtures.

The LRI fosters a sustainable and healthy future through its support of high quality science that can inform effective decision making by industry, regulators, and society.


The following principles are the basis of the LRI program and ensure that the funded research meets the highest quality standards:

  • Scientific Excellence. The best research proposals and most-qualified scientists will be selected for funding.

  • Transparency. Research will be conducted openly and the results will be publicly available.

  • Fair and Unbiased Conduct. Potential conflicts of interest will be rigorously evaluated.

  • Relevance to the Chemical Industry. Research will address the potential health and environmental impacts of chemicals.


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