Scientific Tools and Methods

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The research supported and catalyzed by LRI over the last 20 years has led to the development of a number methods and tools to investigate and characterize toxicity, exposures, dosimetry, and risks. Click on the icons below to access information on the LRI tools and methods that relate to each research area.

RC Epi RC Exposure      RC Env RC MOA      RC Other

LRI Tools and Methods: Epidemiology

RC Epi

Epidemiology is the study and analysis of the patterns, causes, and effects of diseases. Research support from ACC’s LRI has contributed to the epidemiology methods and tools listed below. Click on the hyperlinks to learn more about each method.

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LRI Tools and Methods: Exposure Science

RC Exposure

Exposure science focuses on understanding the fate and transport of chemicals from sources of manufacturing, use and disposal and includes studies of exposure scenarios, behaviors and use patterns related to contact and interactions with, and uptake by, environmental receptors and humans. Research support from ACC’s LRI has contributed to the exposure science methods and tools listed below. Click on the hyperlinks to learn more about each method.

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LRI Tools and Methods: Ecological & Environmental

RC Env

Ecological and environmental science focuses on understanding the potential impacts of chemicals released to environmental media, such as air, water and soil, and how such exposures may influence environmental receptors. Research support from ACC’s LRI has contributed to the ecological and environmental exposure science methods and tools listed below. Click on the hyperlinks to learn more about each method.

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LRI Tools and Methods: Pathways and Mechanisms of Action

RC MOA

Research of toxicity pathways and mechanisms of action of chemicals focuses on understanding the moleciular and biological interactions of chemicals with living organisms and the dose-related relationships of such interactions with cellular and organ-level events in pathways of causally related events that may lead to adverse health effects. Listed below are methods and tools that research support from ACC’s LRI has contributed to. Click on the hyperlinks to learn more about each method.

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LRI Tools and Methods: Technology and Assessments

RC Other

Understanding the potential risk of exposures to chemicals requires integration of scientific evidence from epidemiological studies, laboratory animal investigations, and mechanistic research with knowledge of exposure and dosimetery. ACC’s LRI has contributed to the development and improvement of a wide variety of technologies and assessment methods focused in improving risk-based approaches for evaluating chemicals. Click on the hyperlinks to learn more about each method.

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